Fast Food Restaurant – illustrative photo

Fast Food RestaurantSioux Falls, SD

McDonald's – 5201 South Louise Avenue, Sioux Falls

Open now · closes 10:00 PM

Directions Call

Illustrative photo

Opening hours

Open now · closes 10:00 PM

Weekly opening hours of McDonald's
Monday	6:00 AM – 10:00 PM
Tuesday	6:00 AM – 10:00 PM
Wednesday	6:00 AM – 10:00 PM
Thursday	6:00 AM – 10:00 PM
Friday	6:00 AM – 11:00 PM
Saturday	6:00 AM – 11:00 PM
Sunday	6:00 AM – 10:00 PM

Local time in Sioux Falls: 9:25 PM (CDT). Holiday hours may differ – call (605) 362-6011 to confirm.

Location & directions

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5201 South Louise Avenue
Sioux Falls, SD 57108

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About McDonald's

Looking for a fast food restaurant in Sioux Falls? McDonald's is at 5201 South Louise Avenue, Sioux Falls, South Dakota. It is one of 196 places to eat and drink we list in Sioux Falls.

McDonald's is open 7 days a week, usually 6:00 AM – 10:00 PM. Night owls can stop by until 11:00 PM on Friday and Saturday. Early risers are covered too: doors open at 6:00 AM most days.

You can visit for takeout and drive-through. On the menu: burgers.

Accessibility features: wheelchair accessible. For questions or orders, call (605) 362-6011.

Quick facts

Category: Fast Food Restaurant · Burger
Address: 5201 South Louise Avenue, Sioux Falls, SD 57108
Phone: (605) 362-6011
Hours: Open 7 days a week, usually 6:00 AM – 10:00 PM
Listing updated: September 2026 · Suggest an edit

Popular times (estimated)

6AM

9AM

12PM

3PM

6PM

9PM

Estimated from typical visit patterns for fast food restaurants and this venue’s opening hours – not live data.

Features & amenities

Service options

Takeout
Drive-through

Accessibility

Wheelchair accessible

Amenities

Wi-Fi

Reviews

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Frequently asked questions

What are McDonald's's opening hours?

Open 7 days a week, usually 6:00 AM – 10:00 PM. Monday: 6:00 AM – 10:00 PM; Tuesday: 6:00 AM – 10:00 PM; Wednesday: 6:00 AM – 10:00 PM; Thursday: 6:00 AM – 10:00 PM; Friday: 6:00 AM – 11:00 PM; Saturday: 6:00 AM – 11:00 PM; Sunday: 6:00 AM – 10:00 PM.

Is McDonald's open on Sunday?

Yes, McDonald's is open on Sundays: 6:00 AM – 10:00 PM.

Where is McDonald's located?

McDonald's is located at 5201 South Louise Avenue, Sioux Falls, SD 57108.

What is the phone number of McDonald's?

You can call McDonald's at (605) 362-6011.

Does McDonald's offer delivery or takeout?

Delivery is not listed for McDonald's, and takeout is available. Listed service options: takeout and drive-through.

Is McDonald's wheelchair accessible?

Listed accessibility features: wheelchair accessible.